834
Caspase 1 (Phospho-Ser376) Antibody
Caspase 1 (Phospho-Ser376) Antibody
Gene ID
NCBI Gene Symbol
CASP1
Swiss-Prot No.
P29466
MW (kDa)
29 kDa
Source
Rabbit
OMIM No.
147678
Reactivity
H, M, R
Concentration
1 mg/ml
Target Modification
Phospho
Immunogen Range
342-391
Unigene No.
Hs.2490
French translation
anticorps
Clonality
Polyclonal
Applications
WB IHC ELISA
Modification Sites
H:S376 M:S374 R:S374
Storage / Stability
Stable at -20°C for at least 1 year.
Specificity
Caspase 1 (Phospho-Ser376) Antibody detects endogenous levels of Caspase 1 only when phosphorylated at Ser376.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase 1 around the phosphorylation site of Ser376.
Properties
If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Synonyms
CASP-1; caspase-1; ICE; IL-1 beta converting enzyme; IL-1BC; IL1BCE; interleukin-1 beta convertase; interleukin-1 beta converting enzyme; p45
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.