Adrenergic Receptor beta2 (Phospho-Ser346) Antibody

H

154

ADRB2

P07550

46 kDa

H:S346

Rabbit

109690

1 mg/ml

321-370

Phospho

anticorps

Hs.591251

Polyclonal

WB IHC IF ELISA

Stable at -20°C for at least 1 year.

Beta-2 adrenergic receptor; Beta-2 adrenoceptor; Beta-2 adrenoreceptor; ADRB2; ADRB2R, B2AR;

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Adrenergic Receptor beta2 (Phospho-Ser346) Antibody detects endogenous levels of Adrenergic Receptor beta2 only when phosphorylated at Ser346.

The antiserum was produced against synthesized peptide derived from human Adrenergic Receptor beta2 around the phosphorylation site of Ser346.

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.