PDGF Receptor beta (Phospho-Tyr751) Antibody

 

PDGF Receptor beta (Phospho-Tyr751) Antibody

Size

50 µg

Catalog no.

A7194

Price

325 EUR

Buy at gentaur.com
Gene ID

5159

Swiss-Prot No.

P09619

Source

Rabbit

NCBI Gene Symbol

PDGFRB

Reactivity

H, M, R

MW (kDa)

123 kDa

Concentration

1 mg/ml

Target Modification

Phospho

Immunogen Range

718-767

Unigene No.

Hs.509067

French translation

anticorps

Applications

IHC ELISA

Clonality

Polyclonal

OMIM No.

131440/173410

Modification Sites

H:Y751 M:Y750 R:Y750

Storage / Stability

Stable at -20°C for at least 1 year.

Physical Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Synonyms

CD140b; kinase PDGFR-beta; PDGF-R-beta; PDGFR; PDGFR-beta; PGFRB; platelet-derived growth factor receptor, beta polypeptide

Specificity

PDGF Receptor beta (Phospho-Tyr751) Antibody detects endogenous levels of PDGF Receptor beta only when phosphorylated at Tyr751.

Immunogen

The antiserum was produced against synthesized peptide derived from human PDGF Receptor beta around the phosphorylation site of Tyr751.

Properties

If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.