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Caspase 8 (Phospho-Tyr380) Antibody
Caspase 8 (Phospho-Tyr380) Antibody
Reactivity
Gene ID
841
NCBI Gene Symbol
CASP8
Swiss-Prot No.
Q14790
MW (kDa)
55 kDa
Modification Sites
H:Y380
Source
Rabbit
Concentration
1 mg/ml
Target Modification
Phospho
Immunogen Range
346-395
Applications
WB ELISA
Unigene No.
Hs.599762
French translation
anticorps
Clonality
Polyclonal
OMIM No.
211980/601763/607271
Storage / Stability
Stable at -20°C for at least 1 year.
Specificity
Caspase 8 (Phospho-Tyr380) Antibody detects endogenous levels of Caspase 8 only when phosphorylated at Tyr380.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase 8 around the phosphorylation site of Tyr380.
Properties
If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Synonyms
Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; Caspase-8 precursor; FADD-homologous ICE/CED-3- like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; ICE8; MACH; MCH5; MORT1-associated CED-3 homolog