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Caspase 8 (Cleaved-Asp384) Antibody
Caspase 8 (Cleaved-Asp384) Antibody
Reactivity
Gene ID
841
NCBI Gene Symbol
CASP8
Swiss-Prot No.
Q14790
Source
Rabbit
Target Modification
Cleaved
Concentration
1 mg/ml
Immunogen Range
335-384
Applications
WB ELISA
Unigene No.
Hs.599762
French translation
anticorps
Clonality
Polyclonal
MW (kDa)
47 and 55 kDa
OMIM No.
211980/601763/607271
Storage / Stability
Stable at -20°C for at least 1 year.
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase 8.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Properties
If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Specificity
Caspase 8 (Cleaved-Asp384) Antibody detects endogenous levels of fragment of activated Caspase 8 resulting from cleavage adjacent to Asp384.
Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Synonyms
Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; Caspase-8 precursor; FADD-homologous ICE/CED-3- like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; ICE8; MACH; MCH5; MORT1-associated CED-3 homolog