PGR
Progesterone Receptor (Phospho-Ser294) Antibody
Progesterone Receptor (Phospho-Ser294) Antibody
NCBI Gene Symbol
Gene ID
5241
Swiss-Prot No.
P06401
MW (kDa)
98 kDa
Source
Rabbit
OMIM No.
607311
Reactivity
H, M, R
Concentration
1 mg/ml
Target Modification
Phospho
Immunogen Range
261-310
Unigene No.
Hs.32405
French translation
anticorps
Clonality
Polyclonal
Applications
WB IF ELISA
Modification Sites
H:S294 M:S294 R:S293
Storage / Stability
Stable at -20°C for at least 1 year.
Synonyms
NR3C3; nuclear receptor 3C3; PGR; PRGR; PR
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Specificity
Progesterone Receptor (Phospho-Ser294) Antibody detects endogenous levels of Progesterone Receptor only when phosphorylated at Ser294.
Immunogen
The antiserum was produced against synthesized peptide derived from human Progesterone Receptor around the phosphorylation site of Ser294.
Properties
If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.