TGF beta Receptor II (Phospho-Ser225/250) Antibody

H, M

7048

P37173

64 kDa

Rabbit

TGFBR2

1 mg/ml

Phospho

191-240

anticorps

IHC ELISA

Polyclonal

H:S225 M:S250

Hs.604277/Hs.82028

133239/190182/610168/610380

Stable at -20°C for at least 1 year.

TGF-beta receptor type II; TGFR-2; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TbetaR-II

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

TGF beta Receptor II (Phospho-Ser225/250) Antibody detects endogenous levels of TGF beta Receptor II only when phosphorylated at Ser225/250.

The antiserum was produced against synthesized peptide derived from human TGF beta Receptor II around the phosphorylation site of Ser225/250.

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.