DES
Desmin (Phospho-Ser60) Antibody
Desmin (Phospho-Ser60) Antibody
NCBI Gene Symbol
Gene ID
1674
Immunogen Range
26-75
Swiss-Prot No.
P17661
MW (kDa)
53 kDa
Source
Rabbit
Reactivity
H, M, R
Concentration
1 mg/ml
Target Modification
Phospho
Unigene No.
Hs.594952
French translation
anticorps
Applications
IHC ELISA
Clonality
Polyclonal
Modification Sites
H:S60 M:S60 R:S60
OMIM No.
125660/181400/601419/604765
Storage / Stability
Stable at -20°C for at least 1 year.
Synonyms
CMD1I; CSM1; CSM2; FLJ12025; FLJ39719; FLJ41013; FLJ41793, intermediate filament protein
Specificity
Desmin (Phospho-Ser60) Antibody detects endogenous levels of Desmin only when phosphorylated at Ser60.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized peptide derived from human Desmin around the phosphorylation site of Ser60.
Properties
If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Gene
Desmins or DES proteins detect by anti-desmin antibodies and DES ELISA kits. DSM1 and DSM2 play an important role in Desminopathy. Desmin regulated Myofibrilate Myopathy is a protein filament mutation of muscle proteins.