7124
Recombinant Human TNF alpha
Recombinant Human TNF alpha
Entrez Gene ID
Source
Yeast
Alias'
TNFSF2
Shipping
Ambient
Storage
-20 °C
Product Type
Protein
MW
17.2 kDa
Target
TNF alpha
Form
Lyophilized
Group
recombinants
Additional source
Recombinants or rec. proteins
Description
The Recombinant TNF alpha is a α- or alpha protein sometimes glycoprotein present in blood.
Protein Sequence
VRSSSRTPSD KPVAHVVANP QAEGQLQWLN RRANALLANG VELRDNQLVV PSEGLYLIYS QVLFKGQGCP STHVLLTHTI SRIAVSYQTK VNLLSAIKSP CQRETPEGAE AKPWYEPIYL GGVFQLEKGD RLSAENRPDY LDFAESGQVY FGIIAL (156)
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Gene
Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.