Recombinant Rabbit IL-1 Receptor Antagonist

Yeast

IL-1F3

IL-1RA

Ambient

-20 °C

Protein

17.0 kDa

100009558

Lyophilized

recombinants

Oryctolagus cuniculus

Recombinants or rec. proteins

SGKRPCRMQA FRIWDVNQKT FYLRNNQLVA GYLQGPNAKL EERIDVVPLE PQLLFLGIQR GKLCLSCVKS GDKMKLHLEA VNITDLGKNK EQDKRFTFIR SNSGPTTTFE SASCPGWFLC TALEADQPVS LTNTPDDSIV VTKFYFQEDQ (150)

The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.

Rabbits are used for polyclonal antibody production by kingfisherbiotech. Rabbit antibodies are very stable and can be stored for several days at room temperature. kingfisherbiotech adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.

The antagonist receptor ligand binding will be in contrast with agonist activity. kingfisherbiotech produces more antagonist and receptor related products as 1.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.