NA
Recombinant IGF-1
Recombinant IGF-1
Entrez Gene ID
Source
Yeast
Target
IGF-1
Shipping
Ambient
Storage
-20 °C
MW
7.6 kDa
Product Type
Protein
Form
Lyophilized
Group
recombinants
Alias'
Somatomedin C
Additional source
Recombinants or rec. proteins
Protein Sequence
GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA (70)
Description
IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.